For long-term investors looking to track the U.S. stock market, S&P 500 ETFs are a popular choice. Two of the most widely held options are the Vanguard S&P 500 ETF (VOO) from Vanguard and the SPDR S&P 500 ETF Trust (SPY) from State Street. Using the TipRanks’ ETF Comparison Tool, we have placed VOO and SPY against each other to find the best ETF for investors in 2026. VOO vs. SPY: Key Differences Every Investor Should Know The main difference between VOO and SPY comes down to cost and trading st